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Immunity Is About Protection |
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IMMUNITY - The
resistance of the body to infection, especially resistance due to
antibodies.
Babies have passive immunity from
some outside infections taken onboard from antibodies transferred
from the mother’s blood, through the placenta, and the mother's
milk. So generally the infant's body takes on the protection against the
same ailments that the mother is protected against, as they share the
mother's blood in the womb and from early breast-feeding.
Diseases that the mother
is not protected from, cannot be passed on to their offspring as they will
not exist. Moreover, the baby in turn can give further protection to its own
children, in the same way, but the protection gets weaker at each
generation, unless the person comes into contact with that particular
antigen, which then boosts the immune system against it.
Active immunity
involves the formation of antibodies after exposure to an antigen.
Bacteria or other
microbes, and foreign mass that invade the body, during an infection, are antigens.
The two different kinds of immune response produced by antibodies
involve: white blood cells called T-lymphocytes, that are produced by the
thymus producing cells with antibodies bound to their surface
and are responsible for such reactions as graft rejection.
B-lymphocytes, which produce cells that release free antibodies into
the blood.

IMMUNE SYSTEM
is the complex group of defence responses found in humans, and other
superior vertebrates that help repel disease-causing organisms,
namely - pathogens. Immunity from disease is actually conferred by two
cooperating defence systems, called non-specific,
inherent immunity
and specific, acquired immunity.
Non-specific
protective mechanisms
repel all micro-organisms equally, while the specific immune
responses are tailored to particular types of invaders.
Both systems
work together to thwart organisms from entering and proliferating
within the body. These immune mechanisms also help eliminate
abnormal cells of the body that can develop into cancer.

IMMUNIZATION is the
production of immunity giving cells, by an injection containing antibodies against
a specific disease, such as tetanus or diphtheria. These provide
temporary passive immunity, or by vaccination, which produces a
longer lasting active immunity.
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IMMUNITY
Inside almost every
living creature, especially mammals there is a remarkable piece of
protection machinery called the immune system.
We have not always had such a complex immune
system. It has evolved over millions of years to defend
us against millions of bacteria, microbes,
viruses,
toxins and parasites that can take residence within our bodily system,
which might break through our initial defences,
that is the skin, nose or mouth, and the Spleen.
If we are unprotected and we are in the main
unprotected; we are perhaps only safely protected against less than
1% of the millions of bacteria, microbes,
viruses,
and toxins that lurk within our world.
So being
unprotected may result in us suffering the consequences of many
invasions.
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To fully comprehend
the power of outside forces, consider this, many thousands die every
day on our planet, simply because they, and their immune system lost
the battle for life.
To fully comprehend
the power of the immune system, or the power of the microorganism, consider that once an animal dies
and is left to Mother Nature, with its bodily functions soon ceasing
to work, outside and internal bacteria and insects will invade the body
unabated, and within twelve
months the body will be almost fully decomposed, bar for the
skeleton. The bacteria and maggots will feed on rotting flesh
breaking it down, turning it into various chemicals and gases.
Such battles rage
inside our bodies every day, we either win them, or lose our life.
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Collectively, micro-organisms show remarkable diversity
in their ability to produce complex substances from
simple chemicals and to decompose complex materials to
simple chemicals. An example of their synthetic ability
is nitrogen fixation, the production of amino acids,
proteins, and other organic nitrogen compounds from
atmospheric nitrogen (N2). Certain bacteria and
blue-green algae, the cyano-bacteria, are the only organisms
capable of this ecologically vital process. An example
of microbes' ability to decompose complex materials is
shown by the white and brown rot fungi that decompose
wood to simple compounds, including CO2.
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Obviously then your immune
system does a great job to keep all of that putrefaction
from happening when you are alive. The immune system is
therefore complex, intricate and fascinating.
SKIN
in human anatomy, the covering, or integument, of the body's surface
that both provides protection and receives sensory stimuli from the
external environment. The skin consists of three layers of tissue:
the epidermis, an outermost layer that contains the primary
protective structure, the stratum corneum; the dermis, a fibrous
layer that supports and strengthens the epidermis; and the subcutis,
a subcutaneous layer of fat beneath the dermis that supplies
nutrients to the other two layers and that cushions and insulates
the body.
The epidermis is made
up of living and nonliving layers. Its innermost layers, the basal
and spinous layers, are alive, and they produce cells, called
keratinocytes, that form the dead outer layer, the stratum corneum,
also called the horny layer. Keratinocytes contain the tough,
insoluble group of proteins known as keratins that also make up hair
and nails. The horny layer forms as keratinocytes, which become
thin, hard, and dehydrated and migrate upward to the surface of the
epidermis. The basal layer also contains melanocytes, i.e., cells
that produce the pigment melanin, which imparts color to the skin
and also protects it from the effects of ultraviolet radiation.
Other cells found in the epidermis include Langerhans cells, which
play a role in the body's immune defenses, and Merkel cells, which
are involved in sensory reception. Structures such as hair
follicles, nails, and sweat and sebaceous oil-producing glands are
appendages that develop from the epidermis and extend into the
dermis.
The dermis takes up
the greater part of human skin. It consists primarily of connective
tissue through which an elaborate network of sensory nerves and
blood vessels thread. The major component of dermal connective
tissue is the extra cellular fibrous protein collagen, which
provides strength to the skin and resists deformation and tearing
under stress. Fibres of collagen are organized loosely in the
papillary layer of the dermis, which is adjacent to the epidermis.
In the reticular layer, beneath the papillary layer, the collagen
fibres are denser and more branched. Another fibrous protein,
elastin, which is more flexible than collagen, is found in the
dermis; fibres of elastin help the skin return to its original form
after it has been stretched. Elastin fibres in the papillary layer
also help to anchor the epidermis to the dermis. Surrounding these
fibrous bundles is an extra cellular gel like matrix called ground
substance, which consists primarily of water, ions, and complex
carbohydrates such as glycosaminoglycans that are often attached to
proteins -proteoglycans. Ground substance helps to hold the cells
of the tissue together and allows oxygen and nutrients to diffuse
through the tissue to cells. Three types of cells—fibrocytes,
histiocytes, and mastocytes—are scattered throughout the dermis.
Fibrocytes synthesize collagen, elastin, and ground substance.
Histiocytes are a type of macrophage—i.e., cells that dispose of
cellular debris and invading micro-organisms by engulfing and
destroying them. Mastocytes, or mast cells, are located near blood
vessels; they release substances that elicit such responses as
fever, edema, and pain.
The subcutaneous fat
layer consists chiefly of fat cells - lipocytes, arranged into
collagen-bound lobules. This fat serves as a nutritional storage
depot for the entire body, and it cushions the skin and insulates
the body against temperature extremes.
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The Spleen - Lymphoid
organ located in the left side of the abdominal cavity under the
diaphragm, the muscular partition between the abdomen and the chest.
In man it is about the size of a fist and is well supplied with
blood. As the lymph nodes are filters for the lymphatic circulation,
the spleen is the primary filtering element for the blood.
The spleen is encased
in a thick connective-tissue capsule. Inside, the mass of splenic
tissue is of two types, the red pulp and the white pulp, which do
not separate into regions but intermingle and are distributed
throughout the spleen. The white pulp is lymphoid tissue that
usually surrounds splenic blood vessels. The red pulp is a network
of channels or sinuses, filled with blood, and it is in the red pulp
that most of the filtration occurs.
The white pulp of the
spleen contains such typical lymphoid elements as plasma cells,
lymphocytes, and lymphatic nodules, called follicles in the spleen.
Like the lymph nodes, it reacts to microorganisms and other antigens
that reach the bloodstream.
Phagocytic cells
in both red and white pulp serve to remove foreign material from the
blood and initiate an immune reaction that results in the production
of antibodies. Germinal centres in the white pulp are sites of
lymphocyte production.
The red pulp has a
specialized role in addition to filtration. It is the body's major
site of the destruction of red blood cells, which normally have a
life span of only 120 days. Degenerate red cells are removed from
the circulation in the spleen, and the haemoglobin that they contain
is degraded to a readily extractable pigment and an iron molecule
that is recycled; i.e., used to produce new haemoglobin elsewhere.
In some species the
spleen also acts as a reservoir for blood during periods of
inactivity. When such an animal is aroused for defense or flight,
the capsule of the spleen contracts, forcing additional blood
reserves into the circulation. The human spleen probably does not
have this capability.
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Vancomycin Resistant Staphylococcus Aureus
June
1997
The
publicized finding of a strain of Staphylococcus Aureus showing resistance, or reduced
susceptibility to vancomycin has caused considerable concern, especially since the low level of the
resistance means that such strains may be missed in routine laboratory anti-microbial susceptibility
tests. Dr Keiichi Hiramatsu of Juntendo University, Tokyo, Japan, who described the characteristics
of the vancomycin-resistant strain, has provided a summary and a provisional method for detection
available on EMC's web site for
Anti-microbial Resistance.
An account of his findings will be published in Journal of Anti-microbial Chemotherapy in July
1997.
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Methicillin-resistant
Staphylococcus Aureus (MRSA)?
Methicillin-resistant
staphylococcus Aureus is a bacterial infection resistant to antibiotic Methicillin.
Staphylococcus
Aureus, sometimes referred to simply as "staf" or "staph A" is a common
bacterium found on the skin of healthy people. If staph gets into the body it can cause a minor
infection such as boils or pimples or serious infections such as pneumonia or blood infections.
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MRSA |
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Methicillin-Resistant
Staphylococcus Aureus produces symptoms no different from any other type of Staphylococcus
Aureus
bacteria. The skin will appear red and inflamed around wound sites. Symptoms in serious cases may
include fever, lethargy, and headache. MRSA can cause urinary tract infections, pneumonia, toxic
shock syndrome, and even death.
The
organism Staphylococcus Aureus is found on many individuals skin and
seems to cause no major problems. However if it gets inside the body, for
instance under the skin or into the lungs, it can cause important infections
such as boils or pneumonia. Individuals who carry this organism are usually
totally healthy, have no problems whatever and are considered simply to be
carriers of the organism.
The
term MRSA or Methicillin resistant Staphylococcus Aureus
is used
to describe those examples of this organism that are resistant to commonly used
antibiotics. Methicillin was an antibiotic used many years ago to treat patients
with Staphylococcus Aureus infections. It is now no longer used except as a
means of identifying this particular type of antibiotic resistance.
Individuals
can become carriers of MRSA in the same way that they can become a
carrier of ordinary Staphylococcus Aureus which is by physical contact
with the organism. If the organism is on the skin then it can be passed around
by physical contact. If the organism is in the nose or is associated with the
lungs rather than the skin then it may be passed around by droplet spread from
the mouth and nose. We can find out if and where Staphylococcus Aureus
is
located on a patient by taking various samples, sending them to the laboratory
and growing the organism. Tests done on any Staphylococcus Aureus grown
from such specimens can then decide how sensitive the organisms is to
antibiotics and if it is a Methicillin resistant (MRSA) organism. These test
usually take 2-3 days.
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Can
MRSA be treated?
Yes.
While MRSA is resistant to many antibiotics and can be difficult to treat there are a few
antibiotics that can cure MRSA infections. Patients that are only colonized with MRSA
usually do not require treatment.
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Bacteria
- Microscopic single-celled organisms found wherever life is possible. Generally 0.0001–0.005 mm long, they may be spherical
- coccus, rod like - bacillus, or spiral-shaped - spirillum and often occur in chains or clusters of cells. True bacteria have a rigid cell wall, which may be surrounded by a slimy capsule, and they often have long
whip-like flagella for locomotion and short hair-like pili used in a form of sexual reproduction. A few bacteria can use simple chemical substances, including carbon dioxide from the atmosphere, to manufacture their own nutrients, but most require a source of carbon derived from living organisms (i.e. organic carbon) plus other nutrients for growth. Some bacteria can reproduce every 15 minutes, leading to rapid population growth.

The most important role of bacteria is in decomposing dead plant and animal tissues and releasing their constituents to the soil (see
carbon cycle). Nitrogen-fixing bacteria in the soil or sea convert atmospheric nitrogen gas to nitrites and nitrates, which can then be used by plants (see
nitrogen cycle). Cheese making and fermentation reactions depend on bacteria. Bacteria also play an important part in animal digestion, especially in ruminants. However, certain (pathogenic) species may cause disease while others, such as Salmonella, can cause
food poisoning.
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How
Does Your Body Fight Infection?
Immunity
- The resistance of the body to infection, especially resistance due to
antibodies. Babies have passive immunity from antibodies transferred from the mother’s blood through the placenta. Active immunity involves the formation of antibodies after exposure to an antigen
- bacteria that invade the body during an infection are antigens. The two different kinds of immune response produced by antibodies involve: white blood cells called T-lymphocytes
- produced by the thymus, which produce cells with antibody properties bound to their surface and are responsible for such reactions as graft rejection; B-lymphocytes, which produce cells that release free antibody into the blood.
Leucocyte
- lymphocytes - or white blood cell. A colorless cell found in large numbers in the blood. There are several kinds, all involved in the body’s
defence mechanisms. Granulocytes and monocytes destroy and feed on bacteria and other micro-organisms that cause infection
- see also phagocyte. The lymphocytes are involved with the production of
antibodies.
Phagocyte
- A cell that engulfs and then digests particles from its surroundings: this process is called
phagocytosis. In vertebrate animals, phagocytes are a type of white blood cell that protect the body by engulfing bacteria and other foreign particles.
Immunization is the production of immunity by an injection containing antibodies against specific diseases
e.g. tetanus and diphtheria, which provides temporary passive immunity, or by
vaccination, which produces the longer lasting active immunity.
Antibody
- A protein produced by certain white blood cells -
lymphocytes that reacts with a particular foreign particle e.g. a
bacterium, that has entered the body. The antibody helps to destroy the foreign particle,
known as the antigen. If the same bacteria invade the body in future, many more of the same antibodies are produced, enabling the body to destroy the bacteria very rapidly and so resist infection. This provides the basis of
immunity. Antibodies are also responsible for the rejection of foreign tissue or organ transplants. See also
monoclonal antibody.
Monoclonal antibody
- A type of pure antibody that can be produced artificially in large quantities and used, for example, to distinguish the major blood groups. Mouse lymphocytes producing the required antibody are fused with mouse cancer cells; the resulting hybrid cells multiply rapidly and all produce the same type of antibody as their parent lymphocytes.
Whilst
all this bodily protection sounds wonderful, the problem with MRSA, is
that there is no defense to it, no answer to its attack.
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Blood cells
There are a number of different cell types in circulation in the blood stream. Here's a quick review:
Red cells
carry oxygen to the cells of the body. They are essentially bags of hemoglobin, the oxygen carrying molecule. Hemoglobin binds oxygen to iron atoms, which give the hemoglobin and thus the cells their distinctive red color.
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White cells
(neutrophils) are of several types:
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Polymorphonuclear cells, or "polys" for short, fight bacterial infections by engulfing bacteria and digesting them. They form PUS and are the chief ingredient of an abscess.
Lymphocytes
are the virus killers. There are two types of these:
T-cells
which remember what germs we've been exposed to and how to kill them. T-cells are the key component of the immune system that is missing in AIDS.
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B-cells
that secrete the actual antibodies that attach to viruses and bacteria and identify them as things to be destroyed - rather like tagging the target with a laser so that the smart bomb will home in and blast the target.
Monocytes
are cells that are related to lymphocytes but have a killing and cleaning function. They cruise through the tissues of the body cleaning up debris and killing any bacteria they find. They are often increased in viral infections - a reassuring finding that your doctor may note on your child's blood count.
Eosinophils
are cells which are strongly related to allergy and the recognition of foreign things in the body like parasites.
Basophils
are cells that are also part of the allergy and parasite recognition system.
Platelets
are the cells that plug leaks in the vascular system, the clotting cells.
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Prion
- An an infectious protein particle called a Prion or Prion Protein. These
Prions appear to have the ability to recruit other normal proteins and induce them to alter their structure to become more prions, that act as vehicles of infection. This is quite different from other infectious diseases, commonly caused by bacteria or viruses. Prions are not genetic.
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Goji Berry - Wolfberry
Other names:
Chinese Wolfberry, Lycium Fruit. Tibetan Goji Berry
The name
Tibetan Goji Berry is used in the natural health food market. Berries
from the Goji plant have been grown in the Himalaya region form the
basis of a very large health food market.
Both kinds of
Goji (Lycium barbarum and Lycium chinense) are deciduous woody
perennial plants, grown in the south of China and tends to be somewhat
shorter, while L. barbarum is grown in the north and tends to be
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Goji also
grows on vines in the valleys of the Himalayas in Tibet, and in
Mongolia. The round, red Goji berries are very tender and must be shaken
from the vine rather than picked in order to avoid spoiling. The Goji
fruits are preserved by slowly drying them in the shade, turning them
into a Sultana like fruit. The berry has been eaten locally in the
Himalayan and Tibetan regions for centuries and is celebrated in
festivals. The Goji fruit is nicknamed the "happy berry" because of the
sense of well being it is said to induce.
Goji berries
are important in traditional Chinese medicine (TCM, where they are
believed to enhance immune system function, help eyesight, protect the
liver, boost sperm production, and improve circulation, among other
effects. In TCM terms, Goji berries are sweet in taste and neutral in
nature; they act on the liver, lung, and kidney channels and enrich yin.
They are
nutritionally rich, containing beta-carotene, Vitamins C, B1, B2 and
other vitamins, minerals, high antioxidants, and amino acids. Some claim
the berries contain such nutrients as isoleucine, tryptophan, zinc,
iron, copper, calcium, germanium, selenium, phosphorus, B6, and vitamin
E.
Culinary
uses: As a food, dried Goji Berries may be eaten raw or cooked. Dried
Goji Berry is an ingredient often used in Chinese soups. |
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This apparently amazing stuff tastes good as
soup, or used as a marinade for meats or vegetables, tenderising and
adding its delicate, salty flavour to the ingredients.
It’s hailed as a miracle-working foodstuff –
rich in vitamins and nutrients and good at combating damage done by less
healthy foods like fried meat and tobacco – it’s been hailed by some as
effective against breast cancer and radiation sickness!
Most people in Japan eat the soup at least
once a day.
Previous studies have suggested that soya-rich
foods can help cut women's risk of developing breast cancer
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For centuries it was held that garlic is good
for the blood, though some doubt has been cast upon whether or not this
is true, but the aromatic ingredient has antiviral, antiseptic and
antibiotic properties. The vital sulphuric compounds it contains make it
an essential detoxifier. So it cannot do much harm, notwithstanding its
great taste.
Part of the lily, or alium, family, of which
onions are also a member, garlic is one of the most indispensible
ingredients around, and plays a central role in Mediterranean and Asian
cookery. A bulb composed of many individual cloves enclosed in a thin
white, mauve or purple skin, it's quite fiery, pungent and crunchy when
raw. As it cooks it becomes more mellow and creamy
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